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KMID : 0857020100250010109
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Kosin Medical Journal
2010 Volume.25 No. 1 p.109 ~ p.113
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A case of Hepatosplenic Candidiasis Treated with Caspofungin in a Patient with Acute Myeloid Leukemia
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Park Sang-In
Chung Mi-Hee
Huh Bang
Park Jae-Sun
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Abstract
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Hepatosplenic candidiasis (HSC) or chronic disseminated candidiasis (CDC) is an invasive fungal infection that affects neutropenic patients. Standard empirical therapy consists of the administration of amphotericin B or fluconazole. In many cases, candidiasis is not easily eradicated, despite the adminstration of these drugs. Caspofungin, a member of the new echinocandin class of compounds, may be an effective alternative that has fungicidal against most candida species and fungistatic against aspergillus species. We report a case of hepatosplenic candidiasis developed during chemotherapy for acute myelocytic leukemia and cured with 5 weeks of caspofungin treatment.
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KEYWORD
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Caspofugin, Candidiasis, Leukemia
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